KNIPE LAB
Synthetic organic chemistry @ Queen's University Belfast
Publications
Rationally Designed Helical Peptidomimetics Disrupt alpha–Synuclein Fibrillation
C. E. Bavinton, R. Sternke-Hoffmann, P. C. Knipe, T. Yamashita, A. D. Hamilton, J. Luo and S. Thompson
Chem. Commun. 2022, doi: 10.1039/D2CC00212D
Atropselective synthesis of N-aryl pyridones via dynamic kinetic resolution enabled by non-covalent interactions
Jamie S. Sweet, Ruichen Wang, Panagiotis Manesiotis, Paul Dingwall and Peter C. Knipe
Org. Biomol. Chem. 2022, doi:10.1039/d2ob00177b
Catalytic Enantioselective Synthesis of C–N Atropisomeric Hetero-
biaryls
Chiral, Sequence-Definable Foldamer-Derived Macrocycles
Toyah M. C. Warnock, Sundaram Rajkumar, Matthew P. Fitzpatrick, Christopher J. Serpell, Paul Dingwall and Peter C. Knipe
Chemical Science, 2021, 12, 15632
Enantioselective organocatalytic formal [3+2]-cycloaddition of isatin-derived ketimines with benzylidenemalononitriles and benzylidineindanones
Conor Duffy, William E. Roe, Aislinn M. Harkin, Ryan McNamee and Peter C. Knipe
New J. Chem. 2021, 45, 22034
Atroposelective Synthesis, Structure and Properties of a Novel Class of Axially Chiral N‐Aryl Quinolinium Salt
J. S. Sweet, S. Rajkumar, P. Dingwall and P. C. Knipe
Eur. J. Org. Chem. 2021, 3980
Conformationally Programmable Chiral Foldamers with Compact and Extended Domains Controlled by Monomer Structure
Z. Lockhart and P. C. Knipe
Angew. Chem. Int. Ed. 2018, 57, 8478
Molecular Recognition in Biomimetic Receptors
P. C. Knipe, S. Thompson and Andrew D. Hamilton
in Macrocyclic and Supramolecular Chemistry: How Izatt-Christensen Award Winners Shaped the Field, Reed M. Izatt (Ed.), 2016, John Wiley and Sons, Ltd, Chichester, UK.
Acid-mediated topological control in a functionalized foldamer
P. C. Knipe, S. Thompson and A. D. Hamilton
A Modular Synthesis of Conformationally Preorganised Extended beta-Strand Peptidomimetics
T. Yamashita, P. C. Knipe, N. Busschaert, S. Thompson and A. D. Hamilton
Hybrid Diphenylalkyne-Dipeptide Oligomers Induce Multi-Strand beta-Sheet Formation
J. E. Ross, P. C. Knipe, S. Thompson and A. D. Hamilton
Amphiphilic Oligoamide alpha-helix peptidomimetics inhibit islet amyloid polypeptide aggregation
O. V. Kulikov, S. Kumar, M. Magzoub, P. C. Knipe, I. Saraogi, S. Thompson, A. D. Miranker and A. D. Hamilton
Beta-Strand Mimetic Foldamers Ridgidified through Dipolar Repulsion
E. A. German, J. E. Ross, P. C. Knipe, M. F. Don, S. Thompson and A. D. Hamilton
Ion-Mediated Molecular Switches
P. C. Knipe, S. Thompson and A. D. Hamilton
7. Remote Conformational Control of a Molecular Switch via Methylation and Deprotonation
P. C. Knipe, I. M. Jones, S. Thompson and A. D. Hamilton
A Lewis acid-mediated conformational switch
P. C. Knipe, H. (K.) Lingard, I. M. Jones, S. Thompson and A. D. Hamilton
Redox-Dependent Conformational Switching of Diphenylacetylenes
I. M. Jones, P. C. Knipe, T. Michaelos, S. Thompson and A. D. Hamilton
Enantioselective one-pot synthesis of dihydroquinolones via BINOL-derived Lewis acid catalysis
Phase-Transfer-Catalysed Synthesis of Pyrroloindolines and Pyridoindolines by a Hydrogen-Bond-Assisted Isocyanide Cyclization Cascade
P. C. Knipe, M Gredicak, A. Cernijenko and M. D. Smith
Chem. Eur. J. 2014, 20, 3005
Catalytic Enantioselective Electrocyclic Cascades
E. E. Maciver, P. C. Knipe, A. D. Cridland and M. D. Smith
Chem. Sci. 2012, 3, 537
Asymmetric Electrocyclic Reactions
S. Thompson, A. G. Coyne, P. C. Knipe and M. D. Smith
Chem. Soc. Rev. 2011, 40, 4217
