Publications

tert-Butyl hydroperoxide mediated Wacker-type oxidations: taking advantage of hexafluoro-2-propanol for challenging substrates

Calum Maguire, Qun Cao, Selena C. L. Gilmer, Bill C. Hawkins, Peter C. Knipe and Mark J. Muldoon

Org. Biomol. Chem. 2026, asap

9 Apr 2026

Tandem continuous-flow α-C-H functionalization of pyrrolidine with aryl bromide-derived organolithium reagents

Lara J Nolan, Ailbhe Ryan, Seán Dempsey, Megan Smyth, Tom Moody, Scott Wharry, Karen Fahey, Paul Dingwall, David A Rooney, Jillian M. Thompson, Mark J. Muldoon and Peter C. Knipe

J. Flow Chem. 2026, asap

2 Apr 2026

Rational Design, Synthesis and Characterization of Fluorinated Cyano-Terminated Diester Liquid Crystals Exhibiting the Ferroelectric Nematic Phase

S. Ansari, R. Uttam, N. Yadav, C. Schmiedl, E. Donnelly, Y. P. Panarin, M. R. Fisch*, P. C. Knipe* and J. K. Vij*

ACS Omega, 2026, asap, doi: 10.1021/acsomega.5c11391

16 Mar 2026

Ritter Reactions in Continuous Flow Catalysed by a Solid-Supported Sulfonic Acid Catalyst

Lara J Nolan, Ailbhe Ryan, Seán Dempsey, Megan Smyth, Tom Moody, Scott Wharry, Karen Fahey, Paul Dingwall, David A Rooney, Jillian M. Thompson, Mark J. Muldoon and Peter C. Knipe

Cat. Sci. Tech. 2026, asap

8 Jan 2026

Oxidation of Alcohols and Aldehydes with Peracetic Acid and a Mn(II)/Pyridin-2-Carboxylato Catalyst: Substrate and Continuous Flow Studies

Ailbhe A Ryan, Seán D Dempsey, Megan Smyth, Karen Fahey, Thomas S Moody, Scott Wharry, Paul Dingwall, David W Rooney, Jillian M Thompson, Peter C Knipe, Mark Muldoon

ChemCatChem 2024, asap

1 May 2024

Atropisomeric Foldamers

S. Ansari and P. C. Knipe

Chempluschem 2024, asap

29 Apr 2024

Enhancing the performance for palladium catalysed tert-butyl hydroperoxide-mediated Wacker-type oxidation of alkenes

Matthew N. Blair, Meadhbh Murray-Williams, Calum Maguire, Clare L. Brown, Qun Cao, Hongxin Chai, Yitong Li, Róisín L. O'Hagan, Paul Dingwall, Panagiotis Manesiotis, Catherine L. Lyall, John P. Lowe, Ulrich Hintermair, Peter C. Knipe and Mark J. Muldoon

Cat. Sci. Technol. 2023, 13, 6224

2 Oct 2023

Non-Covalent Interactions Enforce Conformation in Switchable and Water-Soluble Diketopiperazine-Pyridine Foldamers

S. McCann, W. E. Roe, H. E. Agnew and Peter C. Knipe

Angew. Chem. Int. Ed. 2023, 62, e202307180

7 Jul 2023

Continuous-flow transfer hydrogenation of benzonitrile using formate as a safe and sustainable source of hydrogen

Seán Dempsey, Ailbhe A. Ryan, Megan Smyth, Thomas S. Moody, Scott Wharry, Karen Fahey, Andrew M. Beale, Sofia M. Madrigal, Paul DIngwall, David W. Rooney, Peter C. Knipe, Mark J. Muldoon and Jillian M. Thompson.

React. Chem. Eng. 2023, 8, 1559

16 Jun 2023

A spirocyclic backbone accesses new conformational space in an extended, dipole-stabilized foldamer

William E. Roe, Toyah M. C. Warnock and Peter C. Knipe

Comms. Chem. 2023, 6, 71

19 Apr 2023

Continuous Flow Epoxidation of Alkenes Using a Homogeneous Manganese Catalyst with Peracetic Acid

Ailbhe A. Ryan, Seán Dempsey, Megan Smyth, Karen Fahey, Thomas S. Moody, Scott Wharry, Paul DIngwall, David W. Rooney, Jillian M. Thompson, Peter C. Knipe and Mark J. Muldoon

Org Process Res. Dev. 2023, 27, 262

14 Jan 2023

Rationally Designed Helical Peptidomimetics Disrupt alpha–Synuclein Fibrillation

C. E. Bavinton, R. Sternke-Hoffmann, P. C. Knipe, T. Yamashita, A. D. Hamilton, J. Luo and S. Thompson

Chem. Commun. 2022, 58, 5132

29 Mar 2022

Atropselective synthesis of N-aryl pyridones via dynamic kinetic resolution enabled by non-covalent interactions

Jamie S. Sweet, Ruichen Wang, Panagiotis Manesiotis, Paul Dingwall and Peter C. Knipe

Org. Biomol. Chem. 2022, 20, 2392

8 Mar 2022

Catalytic Enantioselective Synthesis of C–N Atropisomeric Hetero-
biaryls

Jamie S. Sweet and Peter C. Knipe

Synthesis, 2022, 54, 2119

Direct download link

Selected for front cover

23 Feb 2022

Chiral, Sequence-Definable Foldamer-Derived Macrocycles

Toyah M. C. Warnock, Sundaram Rajkumar, Matthew P. Fitzpatrick, Christopher J. Serpell, Paul Dingwall and Peter C. Knipe

Chemical Science, 2021, 12, 15632

10 Nov 2021

Enantioselective organocatalytic formal [3+2]-cycloaddition of isatin-derived ketimines with benzylidenemalononitriles and benzylidineindanones

Conor Duffy, William E. Roe, Aislinn M. Harkin, Ryan McNamee and Peter C. Knipe

New J. Chem. 2021, 45, 22034

8 Nov 2021

Atroposelective Synthesis, Structure and Properties of a Novel Class of Axially Chiral N‐Aryl Quinolinium Salt

J. S. Sweet, S. Rajkumar, P. Dingwall and P. C. Knipe

Eur. J. Org. Chem. 2021, 3980

26 Feb 2021

Conformationally Programmable Chiral Foldamers with Compact and Extended Domains Controlled by Monomer Structure

Z. Lockhart and P. C. Knipe

Angew. Chem. Int. Ed. 2018, 57, 8478

7 May 2018

Molecular Recognition in Biomimetic Receptors

P. C. Knipe, S. Thompson and Andrew D. Hamilton

in Macrocyclic and Supramolecular Chemistry: How Izatt-Christensen Award Winners Shaped the Field, Reed M. Izatt (Ed.), 2016, John Wiley and Sons, Ltd, Chichester, UK.

4 Jul 2016

Acid-mediated topological control in a functionalized foldamer

P. C. Knipe, S. Thompson and A. D. Hamilton

Chem. Comm. 2016, 52, 6521

18 Mar 2016

A Modular Synthesis of Conformationally Preorganised Extended beta-Strand Peptidomimetics

T. Yamashita, P. C. Knipe, N. Busschaert, S. Thompson and A. D. Hamilton

Chem. Eur. J. 2015, 21, 14699

16 Aug 2015

Hybrid Diphenylalkyne-Dipeptide Oligomers Induce Multi-Strand beta-Sheet Formation

J. E. Ross, P. C. Knipe, S. Thompson and A. D. Hamilton

Chem. Eur. J. 2015, 21, 13518

10 Aug 2015

Amphiphilic Oligoamide alpha-helix peptidomimetics inhibit islet amyloid polypeptide aggregation

O. V. Kulikov, S. Kumar, M. Magzoub, P. C. Knipe, I. Saraogi, S. Thompson, A. D. Miranker and A. D. Hamilton

Tetrahedron Lett. 2015, 56, 3670

2 Jun 2015

Beta-Strand Mimetic Foldamers Ridgidified through Dipolar Repulsion

E. A. German, J. E. Ross, P. C. Knipe, M. F. Don, S. Thompson and A. D. Hamilton

Angew. Chem. Int. Ed. 2015, 54, 2649

19 Jan 2015

Ion-Mediated Molecular Switches