Rationally Designed Helical Peptidomimetics Disrupt alpha–Synuclein Fibrillation

C. E. Bavinton, R. Sternke-Hoffmann, P. C. Knipe, T. Yamashita, A. D. Hamilton, J. Luo and S. Thompson

Chem. Commun. 2022, doi: 10.1039/D2CC00212D


Atropselective synthesis of N-aryl pyridones via dynamic kinetic resolution enabled by non-covalent interactions

Jamie S. Sweet, Ruichen Wang, Panagiotis Manesiotis, Paul Dingwall and Peter C. Knipe

Org. Biomol. Chem. 2022, doi:10.1039/d2ob00177b


Catalytic Enantioselective Synthesis of C–N Atropisomeric Hetero-

Jamie S. Sweet and Peter C. Knipe

Synthesis, 2022, doi:10.1055/s-0040-1719896

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Chiral, Sequence-Definable Foldamer-Derived Macrocycles

Toyah M. C. Warnock, Sundaram Rajkumar, Matthew P. Fitzpatrick, Christopher J. Serpell, Paul Dingwall and Peter C. Knipe

Chemical Science, 2021, 12, 15632


Enantioselective organocatalytic formal [3+2]-cycloaddition of isatin-derived ketimines with benzylidenemalononitriles and benzylidineindanones

Conor Duffy, William E. Roe, Aislinn M. Harkin, Ryan McNamee and Peter C. Knipe

New J. Chem. 2021, 45, 22034


Atroposelective Synthesis, Structure and Properties of a Novel Class of Axially Chiral N‐Aryl Quinolinium Salt

J. S. Sweet, S. Rajkumar, P. Dingwall and P. C. Knipe

Eur. J. Org. Chem. 2021, 3980


Conformationally Programmable Chiral Foldamers with Compact and Extended Domains Controlled by Monomer Structure

Z. Lockhart and P. C. Knipe

Angew. Chem. Int. Ed. 2018, 57, 8478


Molecular Recognition in Biomimetic Receptors

P. C. Knipe, S. Thompson and Andrew D. Hamilton

in Macrocyclic and Supramolecular Chemistry: How Izatt-Christensen Award Winners Shaped the Field, Reed M. Izatt (Ed.), 2016, John Wiley and Sons, Ltd, Chichester, UK.


Acid-mediated topological control in a functionalized foldamer

P. C. Knipe, S. Thompson and A. D. Hamilton

Chem. Comm. 2016, 52, 6521


A Modular Synthesis of Conformationally Preorganised Extended beta-Strand Peptidomimetics

T. Yamashita, P. C. Knipe, N. Busschaert, S. Thompson and A. D. Hamilton

Chem. Eur. J. 2015, 21, 14699


Hybrid Diphenylalkyne-Dipeptide Oligomers Induce Multi-Strand beta-Sheet Formation

J. E. Ross, P. C. Knipe, S. Thompson and A. D. Hamilton

Chem. Eur. J. 2015, 21, 13518


Amphiphilic Oligoamide alpha-helix peptidomimetics inhibit islet amyloid polypeptide aggregation

O. V. Kulikov, S. Kumar, M. Magzoub, P. C. Knipe, I. Saraogi, S. Thompson, A. D. Miranker and A. D. Hamilton

Tetrahedron Lett. 2015, 56, 3670


Beta-Strand Mimetic Foldamers Ridgidified through Dipolar Repulsion

E. A. German, J. E. Ross, P. C. Knipe, M. F. Don, S. Thompson and A. D. Hamilton

Angew. Chem. Int. Ed. 2015, 54, 2649


Ion-Mediated Molecular Switches

P. C. Knipe, S. Thompson and A. D. Hamilton

Chem. Sci. 2015, 6, 1630


7. Remote Conformational Control of a Molecular Switch via Methylation and Deprotonation

P. C. Knipe, I. M. Jones, S. Thompson and A. D. Hamilton

Org. Biomol. Chem. 2014, 12, 9384


A Lewis acid-mediated conformational switch

P. C. Knipe, H. (K.) Lingard, I. M. Jones, S. Thompson and A. D. Hamilton

Org. Biomol. Chem. 2014, 12, 7937


Redox-Dependent Conformational Switching of Diphenylacetylenes

I. M. Jones, P. C. Knipe, T. Michaelos, S. Thompson and A. D. Hamilton

Molecules 2014, 19, 11316


Enantioselective one-pot synthesis of dihydroquinolones via BINOL-derived Lewis acid catalysis


Phase-Transfer-Catalysed Synthesis of Pyrroloindolines and Pyridoindolines by a Hydrogen-Bond-Assisted Isocyanide Cyclization Cascade

P. C. Knipe, M Gredicak, A. Cernijenko and M. D. Smith

Chem. Eur. J. 2014, 20, 3005


Catalytic Enantioselective Electrocyclic Cascades

E. E. Maciver, P. C. Knipe, A. D. Cridland and M. D. Smith

Chem. Sci. 2012, 3, 537


Asymmetric Electrocyclic Reactions

S. Thompson, A. G. Coyne, P. C. Knipe and M. D. Smith

Chem. Soc. Rev. 201140, 4217